Beta-Hydroxybutyrate: Much more than a metabolite
Abstract The ketone body beta-hydroxybutyrate (BHB) is a convenient carrier of energy from adipocytes to peripheral tissues during fasting or exercise. However, BHB is more than just a metabolite, having important cellular signaling roles as well. BHB is an endogenous inhibitor of histone deacetylases (HDACs) and a ligand for at least two cell surface receptors. …
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